We’ve probably all been there when it comes to having an annoying co-worker. You know — that one co-worker who is either overly arrogant, lazy, or talks your ear off? Even if you consider yourself an easy-going person to work with, you’ve probably encountered that one colleague who drives you up your cubicle walls. After all, what would work be without having a co-worker who drives you nuts? Here are seven ways to handle your most irritating co-workers: 1. Maintain a positive attitude. Honestly, the best thing you can do in this situation is to let the annoying things your co-worker does to roll off your back. Read more.